Investigation on the Stoichiometry of Carbon Dioxide in Isotope-Exchange Reactions with Phenylacetic Acids

Abstract The functionalization of carbon dioxide (CO2) as a C1 building block has attracted enormous attention. Carboxylation reactions, in particular, are major interest for applications isotope labeling. Due to the inexpensive nature CO2, information about its stoichiometric use is generally unavailable literature. Because rarity and limited availability CO2 isotopomers, this parameter concern carbon-isotope We investigated effects stoichiometry labeled on exchange phenyl­acetic acids. Both thermal photocatalytic procedures were studied, providing insight into product outcome incorporation. Preliminary results isotope-dilution carbonate bases carboxylation reactions have also been obtained.